California’s identification and ranking of substances for hazard assessment under Proposition 65 included PFOS and PFDA, PFHxS, PFNA, and PFUnDA and related substances

In March, the OEHHA (Office of Environmental Health Hazard Assessment) selected for hazard assessment several per- and polyfluoroalkyl substances (PFAS) for review and possible listing.  The chemicals are under review by two expert committees: the Carcinogen Identification Committee (CIC) and the DARTIC (Developmental and Reproductive Toxicant Identification Committee).  Under evaluation as carcinogenic and/or reproductive hazards are PFOS and its salts and transformation and degradation precursors; and PFDA and its salts, PFHxS and its salts, PFNA and its salts, and PFUnDA and its salts.

In a summary released this spring, OEHHA listed 22 substances reviewed and ranked by DARTIC from High Priority to No Priority for assessment.  OEHHA has discretion to determine which if any will be considered for listing under Prop 65:

Chemical Recommended Priority
Benzophenone 3 High priority
Bisphenol S (BPS) High priority
Diazinon High priority
Glyphosate and its salts High priority
Perfluorodecanoic acid (PFDA) High priority
Perfluorohexanesulfonic acid (PFHxS) High priority
Perfluorononanoic acid (PFNA) High priority
Imidacloprid Medium/High priority
Acetamiprid Medium priority
Butyl paraben Medium priority
Clothianidin Medium priority
Domoic acid Medium priority
Manganese Medium priority
Methyl paraben Medium priority
Perfluorodecanoic acid (PFUnDA) Medium priority
Titanium dioxide nanoparticles Medium priority
Zearalenone Medium priority
Thiamethoxam Medium priority/No priority
Vinpocetine Medium priority/No priority
Diethyl phthalate No priority
Isobutyl paraben No priority
Propyl paraben No priority

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